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Pathogens & Barriers

Exam code: 5090
Written by: Ashika|Reviewed by: Caroline Carroll|Updated 2 July 2026

Pathogensvideo

Pathogens

Pathogens

  • A pathogen is a disease-causing organism

  • Pathogens are passed on from one host to another and therefore the diseases they cause are known as transmissible diseases

  • Pathogens can be passed on from host to host in different ways, including:

    • Direct contact - the pathogen is passed directly from one host to another by transfer of body fluids such as blood or semen (eg HIV, gonorrhoea, hepatitis B & C)

    • Indirect contact - the pathogen leaves the host and is carried in some way to another, uninfected individual

Methods of transmission table

Method of Transmission

Examples of diseases spread in this way

Droplets in air

Common cold, influenza

Food or water

Cholera, typhoid, dysentery

Touching contaminated surfaces

Athlete's foot, Salmonella (can be transmitted on the feet of flies that land on food that then gets eaten)

Insect bites

Malaria, dengue fever

The Body Defences

The Body Defences

  • The body has several barriers to the entry of pathogens; these barriers can be either mechanical or chemical

    • Mechanical, or physical, barriers make it difficult for pathogens to get past them and into the body

    • Chemical barriers are substances produced by the body cells that trap or kill pathogens before they can get further into the body and cause disease

  • Examples of barriers to the entry of pathogens include:

    • Skin covers almost all parts of the body to prevent infection from pathogens; if it is cut or grazed, it immediately begins to heal itself, often by forming a scab

    • Mucus and hairs in the nose and airways make it difficult for pathogens to get past them and into the airways and lungs

      • Mucus traps pathogens

      • The hairs waft the mucus out of the airways

    • The stomach contains hydrochloric acid which is strong enough to kill any pathogens that are swallowed

  • Other examples include enzymes in tears, and sebum, an oily substance produced by the skin