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HIV & the Immune System

Exam code: 5090
Written by: Ashika|Reviewed by: Caroline Carroll|Updated 2 July 2026

HIV & the Immune System

HIV & the Immune System

  • The HIV virus infects a certain type of lymphocyte in the immune system

  • Normally lymphocytes seek out and destroy pathogens that enter the body, producing antibodies that attach to pathogens, enhancing phagocytic activity

  • However, HIV infects a certain type of lymphocyte and uses the cells’ machinery to multiply

  • This reduces the number of lymphocytes in the immune system, and also the number of antibodies that can be made

  • This decreases the body’s ability to fight off infections, eventually leading to AIDS (Acquired immunodeficiency Syndrome)

  • The weakened immune system is susceptible to infections that would normally have been dealt with by a fully-functioning immune system

    • e.g influenza, pneumonia, skin cancer